Chronic Kidney Disease in Cats (2024)

Chronic kidney disease (CKD), also called chronic renal failure, is long-standing (greater than 3 months) kidney dysfunction that is manifested by dilute urine (urine that is not as concentrated as it should be) and retention of urea (uremia) and other waste products in the body. CKD is a common problem in older cats but can also occur in young and middle-aged cats.

Causes
In many cases, the underlying cause of CKD is never discovered. Identifiable causes include kidney infections and stones, obstruction of the ureter (the tube that carries urine from the kidney to the bladder), incomplete recovery from previous damage to the kidney (such as acute renal failure), polycystic kidney disease (an inherited condition common in long-haired cats), and certain tumors (such as lymphoma). In young cats, congenital kidney disease (such as kidney dysplasia) may be the cause. Kidney stones are more common in middle-aged cats.

Clinical Signs
CKD may be detected on routine screening of blood and urine prior to the onset of signs. Diagnosis at this stage allows treatments to be started that may slow the progression of CKD. Early clinical signs may include increased water intake and urine production, decreased appetite, and nausea. In later stages, vomiting, lethargy, and dehydration may be apparent. Physical examination findings may include dehydration, weight loss or muscle loss, poor hair coat, small or irregular kidneys, and a uremic odor to the breath.

Diagnostic Tests
Initially, a biochemistry panel, complete blood test, and urinalysis are usually recommended. With CKD, kidney function tests, such as blood urea nitrogen (BUN) and creatine, are elevated. Levels of blood electrolytes (potassium) and certain chemicals (phosphorus, calcium) may also be abnormal.

Treatment Options
Currently, no treatments are available that will reverse CKD. The goals of treatment are to slow progression of CKD and treat the clinical signs. Feeding a special kidney diet, which contains less protein and phosphorus, is the most effective method of slowing progression of CKD. Cats eating a kidney diet can live twice as long as those eating a regular maintenance diet. These diets can be started even before signs occur. Control of blood phosphorus levels is also necessary. If dietary changes alone do not accomplish this, drugs to bind the phosphorus in the food can be given with each meal.

If chronic dehydration is present, injections of fluid under the skin (subcutaneous fluids) may be helpful. The frequency varies from daily to twice weekly, and the injections can be given at home.

Potassium supplements may be needed in some cats, as well as drugs to treat excess acid in the blood. Severe, advanced anemia can be treated with hormone injections to stimulate the production of red blood cells, but some cats develop side effects from the hormone the longer it is used. Antacids, such as famotidine, are frequently prescribed for vomiting, and appetite stimulants may be given.

Follow-up Care
Follow-up visits often involve examinations, laboratory tests, and blood pressure measurements (when available). Frequency of visits depends on the severity of CKD, with monthly visits recommended in advanced cases. Cats with early, stable disease may only need to be checked every 3-6 months.

Prognosis
CKD is a progressive disease that slowly worsens, but the rate of progression is highly variable. Cats diagnosed with early disease have an average survival time of 3 years. Those with moderate disease live an average of 2 years. Those with advanced disease generally succumb to CKD within months. Despite these general rates, the survival time of any individual cat is impossible to predict.

Chronic Kidney Disease in Cats (2024)

FAQs

How long can a cat live with chronic kidney disease? ›

Cats classified as stage three at diagnosis survived for an average of 1.86 years (679 days) but with some surviving up to 5.75 years. Cats in stage four kidney disease had a median survival of only 1.16 months (35 days).
...
Diagnosis and prognosis.
StageSerum creatinine mg/dl (μmol/litre)
32.9–5.0 (251–440)
4>5.0 (>440)
2 more rows
May 2, 2017

How fast does chronic kidney disease progress in cats? ›

Chronic kidney failure in cats is a gradual condition that typically develops over several months or even years.

Can cats live with chronic kidney disease? ›

CKD is not a curable or reversible disease, however, with early detection, support and treatment can improve your cat's quality and length of life by slowing progression of the disease. In fact, cats can live for many years with consistent management.

Is kidney disease in cats always fatal? ›

Kidney disease is the number one killer of cats over 14 years of age. Unless they develop another life-threatening disease first, all cats will eventually die from kidney failure.

What are the 3 early warning signs of kidney disease? ›

Here are three signs that could indicate that you are beginning to experience a decline in kidney function.
  • Dizziness and Fatigue. One of the first possible signs of weakening kidneys is the experience of overall weakness in yourself and your overall health. ...
  • Swelling (Edema) ...
  • Changes in urination.

Can a cat's kidney function improve? ›

Lost kidney function cannot be restored, but you can take steps to care for your cat's kidneys and minimize their chances of CKD development or progression.

Is cooked chicken good for cats with kidney disease? ›

As obligate carnivores, cats need species-appropriate proteins that are easily digestible. Proteins such as turkey and chicken are a safe choice for cats with kidney diseases.

How do you slow down kidney disease in cats? ›

Dietary modification is an important and proven aspect of CKD treatment. Studies suggest that therapeutic diets that are restricted in protein, phosphorus and sodium content and high in water-soluble vitamins, fiber, and antioxidant concentrations may prolong life and improve quality of life in cats with CKD.

Is canned tuna good for cats with kidney disease? ›

Tuna is high in phosphorus and while a healthy cat may cope with this, it won't be good for cats with kidney disease.

What should cats with kidney disease avoid? ›

High salt (sodium) diets may increase blood pressure and may worsen kidney damage, so diets designed for pets with kidney disease are low in sodium. You should also avoid feeding high salt treats such as cheese, bread, deli meat, and many commercial dog and cat treats.

What makes kidney disease worse in cats? ›

Chronic stress that raises blood pressure is linked to kidney disease, as well as dental disease, low potassium, and certain diets. The best way to ensure good health for your pet is to: Follow up with twice-yearly wellness examinations where we can screen your meow pal for the disease.

Can you reverse kidney failure in cats? ›

It can happen in cats of any age and typically results from poisons, disorders, diseases, organ failure, medications and other causes. Acute renal failure can often be reversed if caught in time.

Do cats with kidney disease drink a lot of water? ›

Failing kidneys lose the ability to concentrate urine, which is why cats with kidney disease will pee more frequently and will pee larger amounts. Consequently, these cats will need more water to make up for what they lose through urination.

What food is best for cats with kidney disease? ›

Examples include Hill's® Prescription Diet® k/d® (both early and late state diets exist), Royal Canin® Renal Support, Purina® ProPlan® Veterinary Diet NF Kidney Function®, and Rayne Clinical Nutrition™ Adult Health-RSS™.

What foods help repair kidneys? ›

The Best Foods for Kidney Health
  • Dark leafy greens. Dark leafy green vegetables such as kale, spinach, chard, and collard greens are loaded with vitamins A and C, calcium, and many other important minerals. ...
  • Berries. ...
  • Cranberries. ...
  • Sweet potatoes. ...
  • Olive oil. ...
  • Fatty fish. ...
  • Cabbage.

What is the first stage of kidney failure? ›

In Stage 1 CKD, the damage to your kidneys is mild. Your kidneys are still working well, but you may have signs of kidney damage or physical damage to your kidneys. Stage 1 CKD means you have a normal estimated glomerular filtration rate (eGFR) of 90 or greater, but there is protein in your urine (i.e., your pee).

What are telltale signs of kidney problems? ›

What are the Symptoms of Kidney Disease?
  • Changes in urination. Healthy kidneys help filter blood to create urine. ...
  • Fatigue. ...
  • Itching. ...
  • Swelling in your hands, legs, or feet. ...
  • Shortness of breath. ...
  • Pain in the small of your back. ...
  • Decreased appetite. ...
  • Puffiness around your eyes.

Does dry cat food cause kidney problems? ›

While there are many different factors that contribute to your cats renal disease. The most common and most preventable cause is off the shelf commercial dry cat food. The reason is that cats fed exclusively dry food suffer from chronic dehydration, which leads to stress on the kidneys over time.

Is tuna high in phosphorus? ›

Meat, dairy, seafood and fish -- including tuna -- have higher amounts of phosphorus than plant-based foods. Tuna provides around 30 percent or more of your total phosphorus needs for the entire day in a single serving.

How long can a cat live with stage 3 kidney disease? ›

Those cats with IRIS stage II kidney disease survived on average over 1000 days, stage III cats nearly 800 days and stage IV cats only about 100 days. If your cat's diagnosis is low IRIS stage chronic kidney disease, try not to worry. Treatment can help keep your cat around for years to come.

Is CKD painful for cats? ›

A cat suffering from CKD is likely to be experiencing both physical and emotional pain due to the number of side effects associated with the disease; vomiting, dehydration and anorexia for example.

When is it time to put a cat down with kidney failure? ›

If you've witnessed your cat's condition gradually decline, and the blood work is not improving, it's time to make a decision about euthanasia. Questions like, “How much suffering is too much?” will be on your mind. Because you know your cat best, you are the best judge of your cat's quality of life.

What are the symptoms of end stage kidney failure in cats? ›

Symptoms of end stage kidney failure in cats include dull sunken eyes, inability to walk, body odour, incontinence in bladder or bowels, refusal to eat or drink, seizures, confusion, pacing and restlessness, withdrawing, hiding and running away.

How do you prolong a cat's life with kidney failure? ›

Dietary modification is an important and proven aspect of CKD treatment. Studies suggest that therapeutic diets that are restricted in protein, phosphorus and sodium content and high in water-soluble vitamins, fiber, and antioxidant concentrations may prolong life and improve quality of life in cats with CKD.

How can I comfort my cat with kidney disease? ›

Ways To Help Cats with CKD
  1. Diet Modifications. A prescription diet restricting protein and phosphorus may be one of the first changes recommended with early renal disease. ...
  2. Medications. ...
  3. Hydration. ...
  4. Subcutaneous Fluids. ...
  5. Reduce Stress.
Feb 1, 2021

Why do so many cats get kidney disease? ›

A large number of medical problems can cause kidney disease in cats. The most common causes are the resulting damages from toxins, infectious diseases and diseases that impair kidney blood flow. Common toxins to be aware of are ethylene glycol (antifreeze), lily flowers, plants and vitamin D.

Can you save a cat with kidney failure? ›

If acute cat kidney failure is caught early enough, it can be managed. However, chronic cat kidney failure cannot be cured and your vet can only provide palliative care. Depending on your cat's individual case, treatment may include food modification, fluid therapy, dialysis, blood pressure drugs, or a transplant.

Can kidney failure in cats be stopped? ›

Treatment for kidney disease in cats

Acute renal failure in cats (ARF) is potentially reversible if diagnosed early and treated aggressively. A cat with ARF will require admission into the veterinary hospital for intravenous fluid support to correct rehydration, flush out toxins and balance electrolytes.

What are the chances of a cat recovering from kidney failure? ›

Unfortunately, about half of cats that develop acute kidney failure do not survive, and a quarter to half of survivors have permanent damage.

Do cats meow a lot with kidney disease? ›

Kidney disease can cause high blood pressure and, conceivably, excess vocalization. However, these cats usually have other symptoms that show up first, including increased water intake, increased urination and decreased appetite. Another possibility is hyperthyroidism.

What is the best food to feed a cat with kidney problems? ›

Examples include Hill's® Prescription Diet® k/d® (both early and late state diets exist), Royal Canin® Renal Support, Purina® ProPlan® Veterinary Diet NF Kidney Function®, and Rayne Clinical Nutrition™ Adult Health-RSS™.

How do you lower creatinine levels in cats? ›

Stage 1: The creatinine level in the blood test is lower than 1.6, which means that less than 66% of kidney functions have been lost. At this stage, most vets suggest switching the cat to a more kidney-friendly prescription diet that is lower in processed protein.

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