What Causes a Cryptogenic Stroke? Everything to Know (2024)

What Causes a Cryptogenic Stroke? Everything to Know (1)

Medically Reviewed By Susan W. Lee, DO

— Written By Heather Smith RN, BSN

Updated on February 16, 2023

A stroke occurs when the brain does not receive enough blood flow. This may be due to a blood clot or a burst blood vessel. A cryptogenic stroke is when doctors cannot find the cause of the stroke.According to the American Stroke Association, 87% Trusted Source American Stroke Association Highly respected international organization Go to source of strokes are ischemic, which causes include a blocked artery due to a clot. Hemorrhagic strokes are the second most common type of stroke. They happen due to bleeding in the brain.

With a cryptogenic stroke, a doctor may be able to identify whether it is ischemic or hemorrhagic, but they cannot determine the root cause. About 15–40% of all strokes are cryptogenic strokes.

Read on to learn more about cryptogenic strokes. Learn their cause, symptoms, and treatments.

What Causes a Cryptogenic Stroke? Everything to Know (2)

A cryptogenic stroke, also known as a stroke of undetermined etiology, occurs when healthcare professionals cannot determine the cause.

About 30–40% Trusted Source AHA/ASA Journals Peer reviewed journal Go to source of ischemic strokes are cryptogenic. This happens when the artery is blocked.

Several underlying factors may play a role in the cause of a cryptogenic stroke. These include having:

  • atrial fibrillation and other atrial cardiopathies
  • patent foramen ovale, which is a hole in the heart between the two atrial chambers
  • narrowing of the arteries from plaque buildup

Health experts divide cryptogenic strokes into two categories: cryptogenic embolism and other cryptogenic strokes.

Cryptogenic embolism is when doctors see evidence of where blood flow stops in an otherwise typical-looking blood vessel.

“Other cryptogenic” is the term for strokes that do not meet the criteria of a cryptogenic embolism.

Learn more about what can cause a stroke.

What are the symptoms of a cryptogenic stroke?

Cryptogenic stroke symptoms are similar to the symptoms of other types of strokes. They depend on which area of the brain is not getting blood but may include Trusted Source Centers for Disease Control and Prevention (CDC) Governmental authority Go to source symptoms such as:

  • sudden numbness, weakness, or facial drooping on one side of the body
  • sudden confusion, difficulty speaking, or trouble understanding others
  • vision problems
  • sudden dizziness or loss of balance
  • sudden severe headache

Learn more about the warning signs of a stroke.

What are the treatments for a cryptogenic stroke?

When a person has a stroke, the healthcare team’s goal is to quickly identify and treat the source based on the cause Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source.

In the case of a cryptogenic stroke, when the team cannot find the cause of a cryptogenic stroke, treatment focuses on reducing the risk of future blood clots and possible risk factors.

Treatment may include Trusted Source AHA/ASA Journals Peer reviewed journal Go to source:

  • medications to prevent blood clots, such as antiplatelet therapy or anticoagulation
  • managing high blood pressure
  • managing diabetes
  • managing cholesterol
  • maintaining a moderate weight
  • increasing physical activity if necessary
  • smoking cessationif necessary

What can I expect during recovery from a cryptogenic stroke?

The recovery process after a cryptogenic stroke depends on the severity of your stroke and overall health.

Some people may have slight numbness or weakness on one side of the body. Other people may have complete paralysis on one side and other difficulties, such as swallowing, bladder, and bowel control.

Your doctor may recommend physical, occupational, and speech therapies for rehabilitation. Specialists will help you regain functioning as much as possible. They can also teach you modified ways of doing daily activities.

Learn more about recovery after a stroke.

Call 911 or local emergency services for someone experiencing stroke symptoms. The faster treatment is started, the better the outcome.

How do doctors diagnose a cryptogenic stroke?

Diagnosing a cryptogenic stroke can be a complex process. When a person is suspected of having a stroke, doctors first ask about their medical history and perform a physical assessment.

Tests may include Trusted Source AHA/ASA Journals Peer reviewed journal Go to source an MRI or CT scan to look for evidence of an interruption of blood flow to the brain, such as a blood clot or bleeding.

If these tests come back negative, doctors may look at the electrical conductivity and structure of the heart. Lab tests and imaging studies of your blood vessels may also give clues to the cause of the stroke.

If doctors still do not find the cause, they may diagnose your experience as a cryptogenic stroke.

What are the risk factors for a cryptogenic stroke?

A person can have a stroke at any age. However, the following increase your risk of a cryptogenic stroke:

  • heart disease
  • previous stroke
  • family history of stroke
  • diabetes
  • high blood pressure
  • high cholesterol
  • obesity
  • sickle cell disease
  • sedentary lifestyle
  • smoking
  • excess alcohol consumption
  • frequently eating foods high in saturated and trans fats, and cholesterol

What are the possible complications of a cryptogenic stroke?

Falls and difficulties with balance are common complications Trusted Source PubMed Central Highly respected database from the National Institutes of Health Go to source of a stroke. Trouble swallowing, which can lead to aspiration pneumonia, is another complication.

Some people have lasting problems with speaking and understanding language. Others may not be able to control their bowel or bladder.

Depression is also a common complication after a stroke. Watch for signs of depression in your loved one, or speak with your doctor if you are experiencing depression.

Learn more about complications that can occur after a stroke.

Can I prevent a cryptogenic stroke?

Although it may not be possible to prevent a cryptogenic stroke completely, the following Trusted Source Centers for Disease Control and Prevention (CDC) Governmental authority Go to source can reduce your risk:

  • controlling blood pressure and cholesterol
  • managing medical conditions such as diabetes and heart disease
  • quitting smoking if you smoke
  • consuming a diet high in vegetables, fruit, and fiber
  • avoiding foods high in saturated and trans fats, and cholesterol
  • regular exercise
  • quality sleep
  • maintaining a moderate weight
  • limiting alcohol intake

Your doctor can offer more advice on ways to reduce stroke risk.

Summary

A cryptogenic stroke is a stroke of undeterminable cause.

Symptoms of a cryptogenic stroke are similar to other strokes, including weakness on one side of the body and difficulty speaking. If anyone is experiencing symptoms of a stroke, call 911 or local emergency services.

Doctors typically treat cryptogenic strokes with medications to prevent blood clots. They will also suggest managing health conditions that may raise your risk of strokes.

The faster a person experiencing a stroke receives treatment, the better their outcome. It’s essential to seek treatment immediately to decrease the risk of complications.

What Causes a Cryptogenic Stroke? Everything to Know (2024)

FAQs

What Causes a Cryptogenic Stroke? Everything to Know? ›

According to the American Stroke Association , some possible causes of cryptogenic stroke include: patent foramen ovale — a hole that develops between the left and right upper chambers of the heart. atrial fibrillation — an atypical heart rhythm. a fatty buildup of plaque inside the aorta.

What is the most common cause of a cryptogenic stroke? ›

The most frequent vascular causes of CS are complex aortic plaques and Fabry's disease.

Can stress cause a cryptogenic stroke? ›

It is suggested that stress can induce episodic systemic platelet activation and hypercoagulability, which causes transient thrombus formation and subsequent embolization on both the arterial and venous sides of the circulation; the latter requires a PFO to cause a stroke (paradoxical embolism).

What is the life expectancy of a cryptogenic stroke patient? ›

Median survival in patients with cryptogenic stroke was 55 days (interquartile range, 21–240) versus 147 days (interquartile range, 33–735) in patients with known stroke mechanisms (P<0.01).

What is a stroke with no determined cause? ›

In most cases, a stroke is caused by a blood clot that blocks the flow of blood to the brain. In some instances, despite testing, the cause of a stroke cannot be determined. In this case, the stroke of unknown cause is called a “cryptogenic stroke.” It's estimated that about 1 in 3 ischemic strokes are cryptogenic.

What is the treatment for a cryptogenic stroke? ›

Most patients with cryptogenic stroke are treated with a combination of antiplatelet therapy and stroke risk factor reduction— treatments that are not highly effective in preventing recurrent strokes of cardioembolic origin.

What is the cryptogenic stroke pathway? ›

WHAT IS A CRYPTOGENIC STROKE PATHWAY? A Cryptogenic Stroke Pathway is a consistent approach to a follow-up plan and transition of care for patients with a stroke of unknown source. This implementation guide is intended to extend your acute stroke protocol to include a monitoring plan for cryptogenic stroke patients.

How common are cryptogenic strokes? ›

Cryptogenic strokes account for 15-40% of strokes. Each year, approximately 795,000 individuals are diagnosed with a new stroke.

Can emotional upset cause a stroke? ›

A typical answer would be that indeed, extreme physical or emotional stress are risk factors for stroke, but their role as immediate triggers of stroke is unclear. For heart disease, emotional and physical stress are known to provoke ischaemic events, particularly in vulnerable individuals.

Can emotional distress cause stroke? ›

The increased blood flow could also disrupt plaques that might be fragile,” Dr. Sundermann says. Dr. Sundermann says if you live in a chronic or persistent state of stress, there is some evidence of increased stroke risk.

What is the most life threatening type of stroke? ›

Hemorrhagic strokes are particularly dangerous because they cause severe symptoms that get worse quickly. Without fast medical attention, these strokes often cause permanent brain damage or even death. IMPORTANT: A stroke is a life-threatening emergency condition where every second counts.

Can a person live 20 years after a stroke? ›

For example, 79% of people survive 2 years, 61% survive 3 years, …, 5% survive 16 years, and only 1% survive 20 years.

What is the most common cause of death after a stroke? ›

Mortality after first-ever stroke has been reported to be predominantly due to cardiovascular disease (including stroke mortality), but with excess mortality also amongst other non-cardiovascular causes of death compared with a general population [11].

Does your body warn you before a stroke? ›

The warning signs of stroke include: Weakness or numbness of the face, arm or leg, usually on one side of the body. Trouble speaking or understanding. Problems with vision, such as dimness or loss of vision in one or both eyes.

Can your body warn you a month before a stroke? ›

Although strokes frequently happen, warning signals may appear a month before a stroke. Here are some early stroke warning signs that you shouldn't ignore. Numbness or weakness: One side of the body, face, arm, or leg may experience this.

What is the best diet to prevent stroke? ›

Dietary recommendations for patients at risk of stroke

High intake of olive oil and canola oil. Only whole grains. High intake of vegetables, fruit and legumes. Avoid deep-fried foods and hydrogenated oils (trans fats).

What are the signs of a silent stroke? ›

Silent strokes may be accompanied by the following:
  • Issues with cognitive skills and ability.
  • Temporary loss of muscle movement (including the bladder)
  • Sudden lack of balance.
  • Rapid change in personality or mood.
  • Problems with speech.
  • Loss of vision, strength, and sensation.
  • Brief fainting.
Mar 14, 2024

What is the toast criteria for cryptogenic stroke? ›

TOAST defines cryptogenic stroke as stroke not caused by large artery atherosclerosis, cardioembolism, and small vessel occlusion; cryptogenic stroke is also defined as a stroke of undetermined etiology due to two or more causes being identified, negative evaluation, or incomplete evaluation.

Does cryptogenic stroke show on MRI? ›

MRI for carotid plaque imaging can identify nonstenotic ruptured unstable plaque in patients with cryptogenic stroke.

What of cryptogenic stroke patients have underlying AFIB? ›

Systematic reviews assessing the detection of atrial fibrillation with external ECG monitoring in patients after cryptogenic stroke have shown a detection rate of newly diagnosed atrial fibrillation of 5 to 20%.

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