The Neuroprotective Effects of Purslane (Portulaca oleracea) on Rotenone- Induced Biochemical Changes and Apoptosis in Brain of Rat (2024)

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The Neuroprotective Effects of Purslane (Portulaca oleracea) on Rotenone- Induced Biochemical Changes and Apoptosis in Brain of Rat? ›

Overall, the present study demonstrated the neuroprotective role of purslane in the striatum and proposes its prophylactic potential against developing brain damage and Parkinson's disease induction followed by rotenone administration, and that purslane may be considered as a potential neuroprotective agent against ...

The neuroprotective effect of polysaccharides extracted from purslane was investigated against neurotoxicity in vitro (PC12 cells) and in vivo (rats). Treating PC12 cells with polysaccharides extracted from purslane elevated the survival of these cells and attenuated reactive oxygen species (ROS) generation.

Purslane is a traditional herbs which is known for its antioxidant and anti-inflammatory properties. Purslane as an adjuvant therapy may improve inflammation and oxidative stress in NAFLD patients. Effect of Purslane on oxidative stress and inflammatory markers needs more investigations.

Its use as a purgative, cardiac tonic, emollient, muscle relaxant, and anti-inflammatory and diuretic treatment makes it important in herbal medicine. Purslane has also been used in the treatment of osteoporosis and psoriasis.

Non-Toxic Nature of Common Purslane

Common Purslane, scientifically known as Portulaca oleracea, is often found nestled in vegetable gardens and valued for its edible and medicinal qualities.

Purslane also tends to be saltier than other vegetables because of its succulent nature. If you're watching your sodium intake, you may need to limit how much you eat. Otherwise, you could take in way too much salt. If you're pregnant or nursing, it's always important to be extra careful about what you eat.

It is rich in vitamin A which is a natural antioxidant value. It can play role in vision healthy mucus membranes and to protect from lung and oral cavity cancer. Purslane contains the highest content of vitamin A among green leafy vegetables.

Purslane promotes the anti-aging enzyme telomerase which protects the cells DNA repair function acting like a regenerative fountain of youth for your skin. Purslane holds the distinction of highest levels of omega-3 fatty acids of any vegetable.

It is loaded with antioxidants, minerals, omega-3 fatty acids and beneficial plant compounds. Calorie for calorie, purslane is one of the most nutrient-dense foods on earth.

Is purslane anti-inflammatory? ›

(PO) or Purslane is an annual grassy plant that is distributed in many parts of the world, especially the tropical and subtropical areas. PO has some pharmacological properties such as analgesic, antibacterial, skeletal muscle-relaxant, wound-healing, anti- inflammatory and a radical scavenger.

In general, the way to tell portulaca (Portulaca grandiflora) frompurslane (Portulaca oleracea) is that portulaca has cylindrical leaves andpurslane has flat teardrop or ovate shaped leaves.

How is it used? The plant can be eaten cooked as a potherb and the juice can be ingested to treat diverse ailments. The seeds have important medicinal value, since they can lower blood glucose as well as show cyto-toxicity toward certain cancer cell lines (Al Sheddi et al, 2015; Quattrochi, 2012; Duke et al., 2009).

Although this plant can be nutritious, much like wood sorrel, eat it sparingly as it also contains oxalic acid. To maintain a healthy oxalate level, it is recommended to eat less than 23g of purslane a day (6.71-8.69mg/g based on 200-300mg/day).

According to some animal studies, purslane extract has exhibited liver-protective effects. Moreover, evidence from human trials suggests that purslane consumption may improve blood glucose and triglyceride levels.

What is it used for? The leaves contain various active ingredients (mainly alkaloids) that are hallucinogenic, and can cause psychosis, stimulation (euphoria), and sedation as well. Additionally, the phytochemicals contained in the plant have analgesic, astringent, stimulant, and tonic actions.

The more purslane, the more valuable vitamins A and B, Omega-3 fatty acids and minerals, all of which protect against heart attacks and strokes.

Purslane promotes the anti-aging enzyme telomerase which protects the cells DNA repair function acting like a regenerative fountain of youth for your skin. Purslane holds the distinction of highest levels of omega-3 fatty acids of any vegetable.