Science Investigates: Fasting vs. Calorie Restriction? (2024)

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Science Investigates: Fasting vs. Calorie Restriction? (1)

by Cristina Goyanes

July 13, 2017

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Science Investigates: Fasting vs. Calorie Restriction? (2)

People are always on the lookout for quick and easy ways to lose weight, which is why there are approximately 5 billion new diet books written every year — that’s our unscientific, but probably not inaccurate, estimate. Speaking of unscientific, the problem with the plans in these books is their so-called “new” approaches to weight loss haven’t been tested, well, scientifically. And when they get scientists to pay attention, the plans often fail to produce the stellar results they claim.

One weight-loss method that’s gotten a lot of attention lately is fasting, where people go without eating for several hours (usually 16 or more) or even a full day. Search the internet and Reddit boards, and you’ll find passionate devotees talking about the advantages of fasting for weight loss, muscle gain and other benefits, like improved mental clarity. And while there is research to back up some of these claims, much of it is preliminary or was conducted on animals.

Lately, researchers have been looking into fasting more deeply and are starting to fill this knowledge void. A study published this May in the Journal of the American Medical Association: Internal Medicine sought to find out whether fasting was any better or worse at helping people lose weight than a more traditional diet. Here’s what they discovered:

WHAT DID THE STUDY EXAMINE?

The study looked at the effectiveness of two diets:

  1. One was alternate-day fasting, where subjects ate a very small number of calories (25% of their daily energy needs) on “fasting” days, and an excessive number of calories (125% of their daily need) on “feasting” days.
  2. The other program was more like what most of us imagine when we think of dieting: a calorie-restriction model where people aimed to eat slightly less than their energy need (75%) every day.

WHO TOOK PART IN THE STUDY?

One hundred people total: 86 women and 14 men, aged 18–64 (the mean age was 44). They were obese, but did not have metabolic diseases (like Type 2 diabetes or metabolic syndrome). Their cholesterol counts and blood pressure all fell within the normal range. The subjects were divided into three groups — those who were put on an alternate-day fasting plan, those who were put on a calorie-restriction plan and those who received no intervention. Changes in their bodies were rigorously tracked with researchers using a digital scale (DEXA machine) and MRI scanner to record subjects’ weight and body fat throughout.

READ MORE >DEBUNKING THE MYTH OF FASTED CARDIO

HOW LONG DID THE STUDY LAST?

A full year. The first six months were a weight-loss phase, and the second six-months were a weight-maintenance phase.

WHAT HAPPENED?

Both the alternate-day fasting and caloric restriction groups lost about the same amount of weight — the fasters dropped and kept off 6% of their body weight on average, while the calorie-restrictors came in at a 5.3% loss. Those in the fasting group struggled with adherence, however. There were slightly more dropouts in the group (13 of 34 fasters quit, compared to 10 of 35 bowing out of the caloric-restriction group). The fasters often ate more than their target goal on fasting days, while consuming less than the allowed mark on feasting days.

The researchers also monitored the subjects’ cardiovascular health through markers, like their cholesterol counts. That’s where one curious result occurred, which researchers cannot explain: By the end of the second six-month interval, those in the fasting group had experienced an increase in their LDL cholesterol. (LDL is what we think of as the “bad” cholesterol.) The caloric restriction group did not.

WHAT ARE THE TAKEAWAYS?

  • If your goal is to lose weight, fasting is an option you can try. It appears to work about as well as daily caloric restriction. Alternate-day fasting, which this study examined, is one option. Other popular ones include a 12-hour daily fast, a 16-hour daily fast (often called the “Leangains” diet), a 20-hour daily fast (known by many as the “Warrior” diet), or a 24-hour fast once per week.
  • Keep in mind that, prior to this study, a lot of the most compelling research showing body composition benefits of fasting was performed on “hard gainer” young males (i.e. guys who have a hard time building muscle). The results may not translate so well to other populations.
  • One group of people who should be especially careful with fasting is women. The approach can cause a cascade of hormonal issues in women, including thyroid imbalances and menstrual cycle issues.
  • If you try a fasting diet, do so in consultation with your doctor, especially if you have any cardiovascular risk factors like high cholesterol or blood pressure. Monitor both of them closely. And, perhaps most important, pay attention to how you feel throughout. The body often sends signals when something is going right or wrong. It’s our job to tune in to them.
  • Remember that no diet approach is magical. What matters is what works for you.

Tagseating for weight losslosing weightnutrition tips

About the Author

Science Investigates: Fasting vs. Calorie Restriction? (3)

Cristina Goyanes

Cristina Goyanes is a NYC-based freelance editor and writer who covers topics including sports and fitness, health and lifestyle, and adventure travel for various national men’s and women’s magazines and websites. When she’s not feverishly typing stories at her desk, she’s exploring the world, from the Arctic to Antarctica and plenty of countries in between. Follow her adventures and more at CristinaGoyanes.com.

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Science Investigates: Fasting vs. Calorie Restriction? (2024)

FAQs

Is fasting better than caloric restriction? ›

The study, published Monday in the Annals of Internal Medicine, found that people with obesity lost 10 pounds through intermittent fasting, compared to 12 pounds through calorie restriction. The statistical analysis found no significant difference between the two groups' weight loss.

Is there any scientific evidence for fasting? ›

Studies discovered that intermittent fasting boosts working memory in animals and verbal memory in adult humans. Heart health. Intermittent fasting improved blood pressure and resting heart rates as well as other heart-related measurements.

What is the 2 2 2 method metabolism? ›

Smith says the first 2 is for two different types of meals: fatty meals and carb-heavy meals. The second 2 represents non-food related aspects like weekly weigh-ins and introspective journaling, while the third 2 represents exercise consisting of bodyweight and/or high intensity interval workouts.

What the research says about intermittent fasting and weight loss? ›

The Research So Far. A systematic review of 40 studies found that intermittent fasting was effective for weight loss, with a typical loss of 7-11 pounds over 10 weeks. [2] There was much variability in the studies, ranging in size from 4 to 334 subjects, and followed from 2 to 104 weeks.

What is the latest research on intermittent fasting? ›

Research Highlights:

A study of over 20,000 adults found that those who followed an 8-hour time-restricted eating schedule, a type of intermittent fasting, had a 91% higher risk of death from cardiovascular disease. People with heart disease or cancer also had an increased risk of cardiovascular death.

Is fasting or restricting better for weight loss? ›

When compared, time-restricted eating (also known as intermittent fasting) and calorie counting result in similar weight loss, new research shows. The success of the two weight loss strategies may come down to one common thread: fewer calories consumed throughout a 24-hour period.

What do doctors think about fasting? ›

Intermittent fasting is safe for many people, but it's not for everyone. Skipping meals may not be the best way to manage your weight if you're pregnant or breast-feeding. If you have kidney stones, gastroesophageal reflux, diabetes or other medical problems, talk with your doctor before starting intermittent fasting.

Why is 16 hours the magic number for fasting? ›

While both 12-hour and 16-hour fasting can promote fat burning, it's possible that a 16-hour fast may be more effective. This is because the longer fasting period may lead to a greater depletion of glycogen stores, which can trigger higher levels of fat burning.

Is 16 hours fasting enough for autophagy? ›

Studies suggest the process may start when fasting for 12 to 16 hours and increases with fasting time. There are a variety of health benefits that are associated with fasting and autophagy. Some studies say that autophagy starts within 12-16 hours of not eating.

What is the 222 method for weight loss? ›

The “2 2 2” method employs a strategic dietary approach, oscillating between carbohydrate-protein-dense meals and ketogenic, fatty foods. This cycling encourages metabolic flexibility, potentially aiding the body in burning fat more efficiently.

How to improve metabolism? ›

Here are seven simple ways to increase your metabolism.
  1. Include good quality protein in your diet. ...
  2. Nourish your gut microbiome. ...
  3. Swap ultra-processed food for whole foods. ...
  4. Get your caffeine fix. ...
  5. Go to bed earlier. ...
  6. Exercise. ...
  7. Don't lose weight too fast.
Mar 15, 2024

What are the two phases of food metabolism? ›

Metabolism is a balancing act involving two kinds of activities that go on at the same time: building up body tissues and energy stores (called anabolism) breaking down body tissues and energy stores to get more fuel for body functions (called catabolism)

What foods won't break a fast? ›

Foods you can eat while fasting
  • Water. Plain or carbonated water contains no calories and will keep you hydrated during a fast.
  • Coffee and tea. These should mostly be consumed without added sugar, milk, or cream. ...
  • Diluted apple cider vinegar. ...
  • Healthy fats. ...
  • Bone broth.

Is fasting hard on the heart? ›

News outlets recently reported that limiting the time you eat to just eight hours a day, and fasting for the other 16 hours, could lead to a higher risk of dying from heart and circulatory diseases.

What is the best intermittent fasting window to lose belly fat? ›

A 2023 review of research found that the 16/8 method and 16/8 combined with restricting calories were effective strategies for weight control in adults with overweight or obesity. An eating window starting before noon led to greater weight loss than one that began after noon.

Why calorie deficit is better than intermittent fasting? ›

Researchers say that calorie restriction appears more successful than intermittent fasting for weight loss. Over the course of a six-year study, researchers found that people who ate a greater number of large or medium meals during the day were more likely to gain weight.

Does intermittent fasting work or is it just a calorie deficit? ›

Intermittent fasting could be a good way to lose weight without calorie-counting, a new study found. Participants lost the same amount of weight over six months and kept it off for a further six. Weight loss only occurs through a calorie deficit, but fasting could help people stick to one.

Does intermittent fasting do anything besides restrict calories? ›

Dr. O'Donoghue adds, “There have been some really intriguing studies suggesting that a pattern of intermittent fasting may improve your blood pressure, improve your cholesterol, and really lead to weight loss. But at the end of the day, it seems like it's more about what you eat, rather than the pattern of eating.”

Is calorie restriction the best way to lose weight? ›

Replacing high-calorie foods with lower calorie choices and cutting your portion sizes can help you cut calories and improve weight control. For a successful — and lasting — weight management plan, you also need to increase your physical activity.

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