Royal jelly Uses, Side Effects & Warnings (2024)

Generic name: royal jelly [ROY-al-JEL-ee]
Drug class: Herbal products

Medically reviewed by Drugs.com on Sep 29, 2023. Written by Cerner Multum.

What is royal jelly?

Royal jelly is a milky-white secretion produced by worker bees that helps nurture development of the queen bee. Royal jelly is also known as Apis mellifera, Bee Saliva, Bee Spit, Gelée Royale, Honey Bee Milk, Honey Bee's Milk, Jalea Real, Lait des Abeilles, or Royal Bee Jelly.

Royal jelly should not be confused with apitherapy, bee pollen, or bee venom.

Royal jelly has been used in alternative medicine as a possibly effective aid in treating menopausal symptoms. Royal jelly may have been combined with other plants or extracts in a specific preparation to treat this condition.

Royal jelly has also been used to treat hay fever. However, research has shown that royal jelly may not be effective in treating this condition.

Other uses not proven with research have included treating premenstrual syndrome, infertility, high cholesterol, diabetic foot ulcers, stomach ulcer, pancreatitis, liver or kidney disease, asthma, skin disorders, and many other conditions.

It is not certain whether royal jelly is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Royal jelly should not be used in place of medication prescribed for you by your doctor.

Royal jelly is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Royal jelly may also be used for purposes not listed in this product guide.

Related/similar drugs

Ginkgo Biloba, turmeric, milk thistle

Royal jelly side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although not all side effects are known, royal jelly is thought to be possibly safe when taken for a short period of time.

Stop using royal jelly and call your healthcare provider at once if you have:

  • stomach pain with diarrhea that is bloody; or

  • bronchospasm (wheezing, chest tightness, trouble breathing).

Common side effects of royal jelly may include:

  • itching, irritation, or rash when applied to the scalp.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Follow all directions on the product label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use this product if you are allergic to royal jelly or if you have:

Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have:

  • low blood pressure; or

  • skin irritation or swelling.

It is not known whether royal jelly will harm an unborn baby. Do not use this product without medical advice if you are pregnant.

It is not known whether royal jelly passes into breast milk or if it could harm a nursing baby. Do not use this product without medical advice if you are breast-feeding a baby.

Royal jelly is thought to be possibly safe in children when taken for up to 6 months. Do not give any herbal/health supplement to a child without medical advice.

How should I take royal jelly?

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

If you choose to use royal jelly, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

Do not use different forms (pills, liquid, tonic, cream, etc) of royal jelly at the same time without medical advice. Using different formulations together increases the risk of an overdose.

Do not take topical (for the skin) royal jelly by mouth. Topical forms of this product are for use only on the skin.

Call your doctor if the condition you are treating with royal jelly does not improve, or if it gets worse while using this product.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra royal jelly to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking royal jelly?

Avoid taking royal jelly with other herbal/health supplements that can lower your blood pressure. This includes andrographis, casein protein, cat's claw, coenzyme Q-10, fish oil, L-arginine, lycium, stinging nettle, and theanine.

What other drugs will affect royal jelly?

Do not take royal jelly without medical advice if you are using any of the following medications:

  • warfarin (Coumadin, Jantoven); or

  • blood pressure medication.

This list is not complete. Other drugs may interact with royal jelly, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this product guide.

More about royal jelly

  • Compare alternatives
  • Reviews (1)
  • Drug class: herbal products
  • En español

Related treatment guides

  • Herbal Supplementation

Further information

  • Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circ*mstances.

Medical Disclaimer

Copyright 1996-2024 Cerner Multum, Inc. Version: 1.04.

Royal jelly Uses, Side Effects & Warnings (2024)

FAQs

What is the side effect of royal jelly? ›

It's usually well-tolerated. But people with asthma or allergies might experience an allergic reaction. When applied to the skin: Royal jelly is possibly safe when used for up to 6 months. It might cause skin irritation and rash in some people.

Who should avoid royal jelly? ›

Women with estrogen-receptor positive breast cancer should avoid products containing royal jelly as these may stimulate the cancer (3). Patients allergic to bee products should avoid royal jelly (37). For this reason, propolis should also be avoided.

What does royal jelly do to your body? ›

Royal jelly is well known for its protective effects on reproductive health, neurodegenerative disorders, wound healing, and aging.

Does royal jelly cause inflammation? ›

Hence, Royal Jelly is considered to show anti-inflammatory effects by affecting the signaling pathways.

Does royal jelly affect the brain? ›

Studies in rodents have shown that royal jelly treatment improves cognitive functions, reduces oxidative stress, and increases the number of new neurons [2; 3; 4].

Is royal jelly good for kidneys? ›

In line with the current findings, several studies approved the role of RJ in protecting kidneys, decrease injury, decrease oxidative stress and decrease creatinine levels [22-24].

Does royal jelly affect the liver? ›

Taken together, Royal Jelly can directly act on the liver cells by decreasing rather than terminating cholesterol production in the liver. Therefore, RJ has great potential to be a new way to prevent and treat fatty liver disease induced by cholesterol accumulation.

Is royal jelly FDA approved? ›

Medicinal use of this product has not been approved by the FDA. Royal jelly should not be used in place of medication prescribed for you by your doctor.

Can royal jelly cause weight gain? ›

It can help with weight loss

While royal jelly doesn't directly contribute to weight loss, it can be a healthy addition to your weight loss diet because it is rich in nutrients and low in calories. Moreover, it can also increase your energy levels, which can help you take your workouts to the next level.

When should I take royal jelly, morning or night? ›

It can be selected in fresh or lyophilised form, and combined with other hive products such as honey, for example. Ideally, royal jelly should be taken in the morning before breakfast to benefit from its positive properties for vitality and energy throughout the day.

What is the best form of royal jelly to take? ›

Royal Jelly Powder: Stakich Royal Jelly Powder is concentrated and has 3x higher potency than Fresh Royal Jelly. It is easily mixed into smoothies, water or juice and can be stirred into just about anything. We recommend taking 1/4 teaspoon daily of Royal Jelly Powder.

How much royal jelly should you eat? ›

For consumption: Put the royal jelly under the tongue in the morning on an empty stomach and keep it in the mouth as long as possible. For health maintenance, 1-2 grams (approximately ¼ to 1/5 teaspoon) per day. For medicinal use, 4-5 grams (approximately ½ teaspoon) per day.

Who Cannot take royal jelly? ›

Asthma or allergies: Don't use royal jelly if you have asthma or allergies to bee products. It could cause some serious reactions, even death.

What are the disadvantages of jelly? ›

Research also shows that pectin may inhibit dangerous toxins produced by E. coli, a harmful bacteria ( 18 , 19 ). That said, even though jams and jellies may provide some benefits, they're high sugar products, and consuming too much sugar may lead to weight gain, cavities, heart disease, and type 2 diabetes ( 20 ).

Can royal jelly cause diabetes? ›

The results indicated that taking royal jelly may lead to a reduction in the level of blood glucose. Lower glucose levels in the blood are beneficial for people with type 2 diabetes.

Does royal jelly affect hormones? ›

It may also activate proteins that disrupt estradiol dimerization and cause an estrogen-responsive element to increase transcription of reporter genes. As a result, royal jelly can be considered a “weak estrogenic compound,” alleviating menopausal symptoms.

What does royal jelly do for the liver? ›

Taken together, Royal Jelly can directly act on the liver cells by decreasing rather than terminating cholesterol production in the liver. Therefore, RJ has great potential to be a new way to prevent and treat fatty liver disease induced by cholesterol accumulation.

Is royal jelly bad for testosterone? ›

It does, however, protect the heart by lowering triglyceride and lipoprotein levels. Supplementing royal jelly can enhance testicular testosterone production. Animal research suggests it is able to increase estrogen in post-menopausal animals. Royal jelly may also reduce the effects of estrogen in youth.

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