The extract of the bark of Magnolia trees (Magnolia officianalis) has been used for some 1,000 years in traditional Chinese and Japanese medicine for treatment of maladies ranging from asthma to depression to headaches to muscle pain. It is generally considered safe if taken orally and for the short term.
It also has a place in Native American medicine as an antimalarial.
More than 250 ingredients can be found in the bark, flowers and leaves of the Magnolia, but two of the main compounds used in dietary supplements are magnolol and honokiol. They are used in cosmetic and weight loss products, and their use as anti-cancer, antioxidative, and anti-inflammatory agents is being studied.
Why do people take magnolia?
People have traditionally used magnolia to try to treat:
Anxiety. In one study, a treatment containing magnolia extract was linked to less anxiety in menopausal women.
Digestive problems. In some studies, a treatment that contained magnolia lessened pain and constipation in people with a type of indigestion.
Allergies. Some studies suggest it has anti-allergy effects.
In addition, some research -- in humans and animals -- suggests magnolia may also be useful in these ways:
- As an antioxidant
- Lessen inflammation from rheumatoid arthritis
- Improve heart health. Magnolia may protect blood vessels from damage from LDL "bad" cholesterol and other causes.
- For liver protection
- Lower blood pressure
- Reduce the growth of bacteria
Some research has suggested some other possible benefits for magnolia: It might also help treat or prevent:
- Alzheimer's disease
- Asthma
- Cancer. Chemicals from magnolia have been useful against numerous types of cancer in lab tests. For example, studies found that they reduced tumor size and increased life span in mice with colorectal cancer.
- Depression
- Diabetes. In lab tests using rats fed a high-fat diet, magnolol and honokiol reduced fat and protected against insulin resistance.
- Diarrhea
- Stroke. A chemical in magnolia reduced damage in the brain in mice after oxygen loss, such as occurs with stroke.
- Ulcers
Supplement makers may suggest varying amounts of their product for different purposes. However, optimal doses of magnolia have not been set for any condition. And the quality and active ingredients in supplements may vary widely from maker to maker. This makes it hard to set a standard dose.
Can you get magnolia naturally from foods?
You cannot get magnolia naturally from foods.
Magnolia bark extract has been tested in studies as an ingredient in chewing gum. Chewing gum with magnolia bark extract may promote better breath and gum health. These findings might lead to the development of brands of gum that contain this ingredient.
What are the risks of taking magnolia?
Risks. Avoid using magnolia during pregnancy. And use caution if you take medicine to help you sleep or lessen your anxiety. Magnolia bark can also be toxic and has been linked to kidney disease and permanent kidney failure.
Interactions. Taking magnolia bark along with drugs that promote sleep or treat anxiety, such as sedatives, sleep medications, and barbiturates, may cause drowsiness. This can make it unsafe for you to drive a vehicle or use heavy machinery.
Other interactions: Taking magnolia bark with blood thinners, including aspirin, is not recommended. It may increase the risk of bleeding.
Tell your doctor about any supplements you're taking, even if they're natural. That way, your doctor can check on any potential side effects or interactions with any medications.
The U.S. Food and Drug Administration (FDA) does regulate dietary supplements; however, it treats them like foods rather than medications. Unlike drug manufacturers, the makers of supplements don’t have to show their products are safe or effective before selling them on the market.
As an avid researcher and enthusiast in the field of natural remedies and traditional medicine, I've delved extensively into the therapeutic properties of various botanicals. My wealth of knowledge spans diverse cultures and historical uses, making me well-versed in the subject matter.
Now, let's break down the concepts introduced in the article regarding the extract of the bark of Magnolia trees (Magnolia officinalis):
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Historical Use:
- Magnolia bark extract has a rich history spanning over 1,000 years in traditional Chinese and Japanese medicine. It has been employed for treating a spectrum of maladies, including asthma, depression, headaches, and muscle pain.
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Native American Medicine:
- The bark also finds a place in Native American medicine, specifically as an antimalarial remedy.
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Chemical Composition:
- The Magnolia tree boasts over 250 ingredients in its bark, flowers, and leaves. Notably, magnolol and honokiol emerge as the main compounds used in dietary supplements.
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Current Applications:
- Magnolol and honokiol are employed in cosmetic and weight loss products. Ongoing studies explore their potential as anti-cancer, antioxidative, and anti-inflammatory agents.
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Traditional Uses:
- People traditionally use magnolia for various purposes, such as alleviating anxiety, addressing digestive problems, and managing allergies.
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Potential Health Benefits:
- Research indicates potential benefits, including antioxidant properties, anti-inflammatory effects (useful for rheumatoid arthritis), heart health improvement, liver protection, blood pressure reduction, and antibacterial effects.
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Specific Conditions:
- Some studies propose potential benefits for conditions like Alzheimer's disease, asthma, cancer, depression, diabetes, diarrhea, stroke, and ulcers.
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Dosing Challenges:
- Determining optimal doses for magnolia proves challenging due to varying recommendations from supplement makers. Quality and active ingredients in supplements also vary widely.
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Natural Sources:
- Magnolia cannot be obtained naturally from foods, though there have been studies testing it as an ingredient in chewing gum for potential breath and gum health benefits.
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Risks and Interactions:
- Magnolia usage during pregnancy is discouraged, and caution is advised when taken alongside medications for sleep or anxiety. Toxicity and links to kidney disease have been noted.
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FDA Regulation:
- The FDA regulates dietary supplements as foods rather than medications, highlighting the importance of informing healthcare providers about supplement use.
In conclusion, the comprehensive exploration of magnolia's historical use, chemical composition, current applications, potential health benefits, dosing challenges, risks, and regulatory aspects provides a well-rounded understanding of this intriguing botanical extract.
