Homemade Mouse Poison: 7 Tried And Tested Recipes (Including One That Doesn't Work) (2024)

We’ve been sharing our house with a multitude of rodents for years; our old house seems to double up as a mouse condominium.

While I’m not keen on using poison, fearing it might kill something other than a pesky rodent, I’m reaching the end of my tether now. I’m still determined to use natural repellants and humane traps as far as possible, but decided I’d look into the possibility of poison as a backup plan.

The following recipes all use common household products as the bait to entice the mouse and the poison that will eventually kill it.

Note: Many of these substances are as appealing to pets and small children as they are to rodents, so make sure you distribute your poison carefully and keep it out of reach.

7 Tried And Tested Recipes For Homemade Mouse Poison (Including One That Doesn’t Work)

#1 Baking Soda

Homemade Mouse Poison: 7 Tried And Tested Recipes (Including One That Doesn't Work) (1)

Due to its versatility, most homes have some baking soda stored in the kitchen. As well as being used as a cleaning, anti-acid, and leavening agent, baking soda is a surprisingly effective mouse poison.

Rodents can’t expel carbon dioxide as humans can, so when the bicarbonate in the baking soda reacts with the acids in the rodent’s stomach and produces carbon dioxide, the gas builds up inside the digestive system. Eventually, it will cause a blockage or rupture and kill the mouse.

Mice don’t naturally sit down to a meal of baking soda, so you’ll need to combine it with something appetizing to spark their interest. You can use any of the following as bait for your baking soda poison:

  • Peanut butter – mix with baking soda and then roll into balls and place around your home
  • Flour and sugar – mix equal parts of sugar, flour, and baking soda. Leave in a shallow dish.
  • Cocoa powder – chocolate is difficult for anyone to resist, including mice. Combine equal amounts of cocoa powder and baking soda, and then add a little sugar to sweeten the deal.

While baking soda is safe for children and pets, it’s not particularly humane. Few poisons are, I suppose.

Larger mice and rats also need to consume a considerable amount of baking soda before it kills them, which means you could witness ailing mice stumbling around your house.

#2 Aspartame

Homemade Mouse Poison: 7 Tried And Tested Recipes (Including One That Doesn't Work) (2)

Aspartame is an artificial sweetener that’s readily available and very affordable. Although considered safe for human consumption, research has shown that aspartame, along with a similar substance known as neotame, is “toxic to the digestive gut microbes of mice.”

Mix one sachet of aspartame sweetener, like this one, into one teaspoon of peanut butter. Roll the mixture into two balls of equal size and place them in strategic positions around your home. Attracted by the irresistible scent of peanut butter, mice will gobble this mixture up and die soon afterward.

It takes a while for aspartame to take effect, so if you’re impatient like me, you might want to combine it with something faster-acting, like instant mashed potato.

#3 Instant Mashed Potato Flakes

I’ve always maintained that instant mashed potato is closer to lethal poison than food, and it seems that, for mice, at least, this is true.

This non-toxic approach to poisoning mice is one the safest, especially if you have pets. Few cats or dogs will tuck into a dish of instant mashed potato flakes, but mice seem more than happy to gorge themselves on it.

Once they’ve eaten their fill, they become extremely thirsty. As they drink, the water causes the mashed potato flakes to expand in the mouse’s stomach, killing them instantly.

Sprinkling a sachet of artificial sweetener over the mashed potato flakes makes them even more appealing to mice and will help ensure they eat enough of the substance to seal their fate.

#4 Cement Mix

While this isn’t something everyone has in their kitchen, it is easily available and very effective, assuming you can persuade a mouse to eat it. If a mouse does ingest this, it will quickly harden as it comes into contact with the animal’s digestive juices.

Mix the powder with something tempting, like peanut butter or cocoa powder, for the cement mix to work effectively. Peanut butter works well as it makes the mixture malleable, so you can roll it into balls and place it strategically around the house.

As cats and dogs are just as keen on peanut butter as the rest of us, this homemade mouse poison is not recommended if you have pets.

#5 Plaster of Paris

Homemade Mouse Poison: 7 Tried And Tested Recipes (Including One That Doesn't Work) (3)

If you can’t get your hands on cement mix, plaster of Paris will work just as well. An alternative approach is to combine plaster of Paris or cement mix with cornflour and then add milk or water to form a dough. Knead for a minute or two before rolling into balls and placing them around the house.

Both the cement mix and plaster of Paris will harden after a few days of exposure to the atmosphere and must be replaced regularly.

#6 Boric Acid – Doesn’t work!

According to some, boric acid is one of the best and most effective poison recipes out there. Others disagree, saying it causes only “developmental toxicity.” In other words, while it can harm a rodent’s unborn fetuses, it won’t eliminate your current mouse problem.

You can still use it to dispose of co*ckroaches and ants, but it’s not worth getting if the mouse is your only enemy.

#7 Vitamin D-3

Homemade Mouse Poison: 7 Tried And Tested Recipes (Including One That Doesn't Work) (4)

While Vitamin D may be essential for human health, it can be fatal to other animals, including rodents. The active ingredient, cholecalciferol, is found in many vitamin D-3 supplements and a multitude of rodent poisons.

Vitamin D-3 is a fast-acting poison that causes such high calcium and phosphorus levels in the mouse’s body that it results in kidney failure, heart problems, and bleeding. It’s so effective that it’s been turned into a spray to tackle New Zealand’s “super rats.”

I found a random fact that claimed you would need around 100,000 IU of vitamin D3 to have a 50% chance of killing an 80 oz rat. As most rodents we get in our homes weigh between 0.6 to 17 oz, a single 5000 IU tablet should be enough to make a decent dent in the population.

Crush up the tablet, empty the capsule’s contents, and mix it with peanut butter. Place small balls around the house and wait for a couple of days.

It’s tempting to think of vitamins as relatively benign substances, but vitamin D-3 is toxic to dogs, cats, and children, so be sure you keep it out of reach.

Read more about homemade rat poison.

Mouse Poisons Recap

Most of these recipes for homemade mouse poison will make a dent in any problematic infestation. Some, like instant mashed potato flakes, are even safe to use around pets and children. They won’t even present a threat to wild birds and animals.

None are particularly pleasant for the vermin, and if you want to find a more humane way of dealing with a mouse invasion, try some of the tips I explored when figuring out how to rodent-proof my food storage. Also read:

  • How to make a DIY bait station Can you eat mice? How to make a bucket mousetrap
  • Homemade Mouse Poison: 7 Tried And Tested Recipes (Including One That Doesn't Work) (2024)

    FAQs

    What household ingredient kills mice? ›

    Instant Potato Powder – Mice also eat potato powder, but it's actually lethal for them. Once the powder enters their bodies, the flakes swell inside their intestines until they die.

    What is the best active ingredient in mouse poison? ›

    Generally, the most effective rodent poisons are single-dose poisons such as bromethalin, zinc phosphide or brodifacoum. They contain a highly lethal dose of these poisons to ensure that the mice that consumed it will die within a matter of hours.

    What kills mice asap? ›

    Zinc phosphide is an acute toxicant that causes the death of a house mouse within several hours after a lethal dose is ingested. It appears to be the fastest way of getting rid of mice by reducing their population.

    What liquid kills mice? ›

    LIQUA-TOX ® II is a liquid concentrate containing the active ingredient, diphacinone, that kills rats and mice.

    Does vinegar really get rid of mice? ›

    While it won't eliminate the mice indoors, vinegar could help repel the pests. However, don't solely rely on vinegar as your chosen pest control solution. Even if you manage to keep mice away from the kitchen, bedroom, or living rooms, they can still head toward other areas of your home to bed down and breed.

    What mouse bait do professionals use? ›

    Contrac Blox (Bromadiolne) Contrac Blox is one of the most widely used mouse baits among professional pest control experts.

    How do you make homemade rat mouse poison? ›

    For this poison, combine 1 cup of flour or cornmeal with 1 cup of sugar and a powdered chocolate mix then add 1 cup of baking soda. Mix it very well. Fill some jar lids with the poison and put it where you can find rat droppings. Monitor the area until you no longer see any sign of rat infestation.

    What is an effective mouse poison? ›

    The most popular type of rodenticide is called an anticoagulant. This prevents the mouse's blood from clotting, causing internal bleeding that eventually kills the rodent. Other types of mouse poison include vacor, yellow phosphorus, strychnine and arsenic.

    Does salt kill mice? ›

    Salt is one of the most effective natural methods to get rid of rodents permanently, like mice. Mice are not too fond of salt. So, to kill them, you can concoct a salt-based recipe that the mouse will find difficult to digest. You can, for example, use gypsum and flour in equal parts and incorporate salt into it.

    What home remedies do mice not like? ›

    Cotton balls dabbed with peppermint oil can work well to repel mice, as can dried mint sachets. Just place oil-soaked cotton or mint-scented sachets in problem areas, refreshing as often as needed. For a longer-lasting solution, try a ready-to-use repellent with essential oil technology.

    How to get rid of field mice permanently? ›

    How to Eliminate Field Mice In Your Yard
    1. Set Baited Traps.
    2. Use Poison.
    3. Use Mice Deterrents.
    4. Recruit Natural Predators.
    5. Seal Rodent Entry Points.
    6. Remove Food Sources.
    7. Block Rodent Burrows.
    8. Clean Up and Modify Your Yard.

    What do mice hate the most? ›

    13 scents that mice hate and can help you to keep them away
    • Cinnamon. This has a strong and spicy aroma that mice probably hate. ...
    • Vinegar. Mix some water and vinegar in a spray bottle to mist any areas where they have been seen more often.
    • Dryer sheets. ...
    • Cloves/clove oil. ...
    • Peppermint oil. ...
    • Teabags. ...
    • Mint toothpaste. ...
    • Ammonia.
    May 25, 2022

    Why are the mice eating the poison but not dying? ›

    Death from anticoagulant rodenticide poisoning takes longer than you might think. Rodents that consume anticoagulant poisons do not die immediately. The poison is designed to block the vitamin K cycle which is important in clotting the body's blood, often resulting in a slow death.

    What smell will make mice go away? ›

    The strong scent of peppermint is overwhelming to mice. Similarly, essential oils such as eucalyptus oil, bergamot oil, clove oil, and cinnamon oil are potent in keeping mice at bay. One study noted that eucalyptus oil applied once a day was more effective as a rat repellant than once a week.

    Are any foods poisonous to mice? ›

    Grapes, raisins, rhubarb and walnuts are poisonous to mice and lettuce can cause them to have diarrhoea. Wild mice find food by foraging and so a portion of daily food that is provided for pet mice should be scattered in a cage to encourage this foraging behaviour.

    What kind of vinegar kills mice? ›

    White vinegar is your best bet, but apple cider vinegar is also effective. More important than strength and cost, these are the safest options available.

    What is the best homemade mouse repellent? ›

    Peppermint oil, cayenne pepper, pepper and cloves.

    Mice are said to hate the smell of these. Lightly soak some cotton balls in oils from one or more of these foods and leave the cotton balls in places where you've had problems with mice.

    What chemical do mice hate? ›

    Mothballs are an inexpensive and easy way to keep mice away. Mice hate the smell of mothballs, which is why they do not like to live in areas that house them. Mothballs are made from naphthalene, a chemical that has a strong odour when it is heated up.

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