Excessive Salivation and Photosensitization in Horses: Clover Identified - Kentucky Equine Research (2024)

By Kentucky Equine Research StaffExcessive Salivation and Photosensitization in Horses: Clover Identified - Kentucky Equine Research (1)

Horses love to munch on clover, a sweet legume, but did you know that overconsumption of certain types of clover can potentially be toxic to horses? Different clovers present different challenges for horses.

While healthy stands of white and red clover are not toxic to horses, these plants might harbor a fungus that manifests during stressful growing conditions, such as drought. This fungus produces a harmful mycotoxin. The most common fungus to infect white and red clover is known as “black patch” because of the bronze or black spots it forms on plant stems and leaves. The fungus contains slaframine, a toxin that stimulates the salivary glands and causes excessive drooling, known as “slobbers.” While slaframine is not fatal, horses should be removed from fields if they show signs of slobbers.

A different health concern is associated with alsike clover. Signs of alsike clover toxicity are sensitivity to sunlight, known as photosensitivity, and big liver disease, though the causative agent is unknown. Photosensitivity most often occurs when a horse consumes wet alsike clover. If the horse’s skin is damp or wet, the alsike clover may cause lesions or sores. Swelling of the tongue is also a concern and, at worst, may cause difficulty in chewing or swallowing. Sunburn and reddened skin around the muzzle or unpigmented areas are signs of photosensitivity. Long-term overconsumption of alsike clover may result in an enlarged liver, the result of tissue remodeling and being replaced with connective tissue, which causes progressive loss of liver function. The horse may develop yellowing of the eyes and gums as well as unexplained weight loss.

Other varieties of clover, such as sweet clover (Melilotus species) and crimson clover (Trifolium incarnatum), may also cause health problems, with toxicity signs including slobbers, colic, bloating, diarrhea, weakness, abnormal heartbeat, and abortion in pregnant mares.

The immediate treatment for clover toxicity is to remove the affected horse from grazing areas that contain the plant. Other cures or treatments are unknown. Mowing affected fields may help, but removing horses from the source is the best plan of action. Frequently, symptoms resolve quickly once the horse is removed from the clover, but don’t hesitate to contact your vet for an evaluation. If your pasture is overrun with clover, you may need to renovate and reseed it with a pasture mix appropriate for horses.

Consumption of most clover grown in normal environmental conditions is not harmful to horses, especially when it’s one of many plants flourishing in a grazing area. In some instances, clover is impossible to avoid in a pasture. If your horse takes a few bites of clover, especially when mixed with other pasture plants, it is unlikely to produce an adverse reaction. Each horse may also have a different threshold for tolerance before signs of toxicity appear. Your veterinarian should be consulted immediately for an evaluation and diagnosis if any unusual signs appear. Keep a close eye on your horse during grazing season, and check your pastures for signs of potentially toxic plants.

Unsure what pasture plants might be harmful to your horses and ponies? Ask a Kentucky Equine Research nutrition advisor for assistance.

Excessive Salivation and Photosensitization in Horses: Clover Identified - Kentucky Equine Research (2024)

FAQs

What causes excessive salivation in horses? ›

This excessive salivation usually results from horses eating clover infected with Rhizoctonia leguminicola fungus. The fungus produces slaframine, an irritant that makes horses salivate heavily. Unless it's excessive, this overproduction of saliva isn't harmful, and will disappear as the clover becomes dormant.

Does white clover cause horses to slobber? ›

If harboring sufficient fungal loads, white clover, alsike clover, alfalfa, ladino, and lespedeza can induce slobbering. The fungus produces slaframine, and it is this mycotoxin that actually provokes the extreme salivation.

What effects does clover have on horses? ›

Clover's energy, protein and fiber content make it a good feed source for horses. Mold-infected clover can cause slobbers, liver damage and bleeding in horses. Mold grows when the temperature is above 80 F and the humidity is above 60 percent. Bleeding only happens in horses eating moldy sweet clover hay.

Why does clover make horses salivate? ›

The fungus produces a toxin called slaframine that stimulates the salivary glands of horses causing them to drool - sometimes in alarming quantities. If the fungus is growing on red clover that is baled for hay, it will persist and can cause horses to drool when they consume the hay.

What is the treatment of excessive salivation? ›

Traditional treatment options include daily oral medications to diminish saliva production, periodic injections of a medication called Botox for temporary reduction in saliva production, or a variety of open surgical procedures to remove some salivary glands or disconnect others from the mouth.

How do you stop uncontrollable salivation? ›

The best ways to stop drooling
  1. Change sleeping positions. Share on Pinterest Certain sleeping positions may encourage drooling. ...
  2. Treat allergies and sinus problems. ...
  3. Take medication. ...
  4. Receive Botox injections. ...
  5. Attend speech therapy. ...
  6. Use an oral appliance. ...
  7. Have surgery.

What happens if a horse eats too much clover? ›

Horses with alsike clover poisoning may show signs of liver disease; they become nervous, go off feed and show signs of colic. They may also pass brown urine and clay-coloured manure. A horse that eats a large amount of toxin at one time can die from acute liver failure.

What happens when horses eat too much clover? ›

Long-term exposure to the alsike clover may lead to big liver syndrome, which is the progressive destruction of the liver. Symptoms of liver failure due to alsike clover consumption include loss of appetite, weight loss, depression, jaundice, colic and death.

Can clover cause laminitis? ›

Try to reduce the amount of clover in your sward year on year. This very early season high sugar grass can easily set off laminitis in sensitive animals due to the effect that is has on blood glucose and therefore circulating insulin levels.

How do I get rid of clover in my horse field? ›

Generally, herbicide application is recommended while clover is actively growing and before it gets too large. Treatment can also be done in the autumn while it is still green. Care should be taken to keep horses off pasture for at least a month after spraying and preferably until the dead plants have fully decomposed.

Can clover cause laminitis in horses? ›

Clover and alfalfa are dangerous for horses who are susceptible to laminitis. True. Clover and alfalfa contain relatively high levels of sugars and starch, both in pasture and as part of hay. These nutrients can start the chain of events that leads to digestive laminitis.

Does clover cause liver damage in horses? ›

When mold-infected clovers are ingested by horses, photosensitivity (sunburn) and liver damage can occur. Sunburn of non-pigmented skin, and also discharge of the mucous membranes of the mouth, eyes, and vulva, are often the first noticeable signs.

What stimulates saliva production in horses? ›

Ingestion of slaframine stimulates secretion of saliva, sometimes to the point that copious amounts escape the mouth when opened.

How long do slobbers last in horses? ›

The fungus produces the mycotoxin slaframine which causes the slobbers. It can be present on both pasture and in stored dry hay. The fungus persists on infected fields from year to year. Slaframine will persist in stored hay for 10 months or more; though its biological activity decreases.

Is clover high in sugar for horses? ›

Clover can be very high in sugar and starch and is not a good forage for horses with EMS. Thick, properly fertilized grass will keep clover from taking over.

What medications can stop excessive salivation? ›

Your physician may prescribe certain medications to control saliva.
...
They are in the order most often used.
  • Glycopyrrolate (Robinul) 1-2 mg. ...
  • Propantheline (Pro-Banthine) 15 mg. ...
  • Amitriptyline (Elavil) 10 mg. ...
  • Nortriptyline HCL (Pamelor) 10-25 mg.

What medical condition causes excessive salivation? ›

Medical conditions such as acid reflux and pregnancy can increase saliva production. Allergies, tumors, and above-the-neck infections such as strep throat, tonsil infection, and sinusitis can all impair swallowing.

What medications can cause excessive salivation? ›

Medications that can cause overproduction of saliva include:
  • aripiprazole.
  • clozapine.
  • pilocarpine.
  • ketamine.
  • potassium chlorate.
  • risperidone.
  • pyridostigmine.

What is a natural treatment for excessive salivation? ›

Home remedies: Drinking plenty of water can reduce saliva production. Tooth-brushing and rinsing with mouthwash can also temporarily dry out the mouth.

What is the best clover for horses? ›

Common white clover and Ladino white clover are the most popular legumes for horse pastures. Although alfalfa is commonly recommended, it is seldom found in pasture mixes. Red clover is also commonly recommended but most horse owners avoid it because it can cause the slobbers.

Is clover a good feed for horses? ›

Red clover has always been regarded as a most acceptable clover for horses because of its summer growth habit. Always select a low oestrogen variety as infertility has been reported in broodmares grazing high oestrogen varieties. Sub clover is a self-regenerating annual with winter spring growth habit.

What clover is best for hay? ›

Red clover is effective as a pasture legume and for hay. It can withstand more shading in the seedling stage than most other legumes, making it easy to establish in grass sods.

Does clover give horses diarrhea? ›

Other varieties of clover, such as sweet clover (Melilotus species) and crimson clover (Trifolium incarnatum), may also cause health problems, with toxicity signs including slobbers, colic, bloating, diarrhea, weakness, abnormal heartbeat, and abortion in pregnant mares.

Which clover is toxic to horses? ›

Alsike clover should not be fed to horses in greater than 5% of the feed. Seed mixes intended for horse pastures and hay should not contain alsike clover. Horse owners should be able to recognize the different clovers so that alsike clover poisoning can be prevented.

What is the best hay for horses? ›

Alfalfa, white clover, red clover and birdsfoot trefoil are common types of legumes, with alfalfa being the most popular choice. Benefits: Legumes are higher in protein and calcium than grass hay, and may also provide more energy and a higher level of total digestible nutrients, such as vitamin A.

Does Cinnamon help laminitis? ›

An overweight horse, or one suffering from laminitis, may not have a magnesium deficiency, but adding 30g of cinnamon to its morning feed, and hanging a good mineral lick in the stable to provide magnesium, can correct any such shortage.

What is the best thing to give a horse with laminitis? ›

For a laminitic prone horse/pony, low sugar roughage sources may include Teff hay, Rhodes grass hay, lucerne hay, beet pulp or soaked grass hay.

What are the first signs of laminitis? ›

10 Early Warning Signs of Laminitis
  • A strong/bounding digital pulse. ...
  • A hoof that's hot for hours. ...
  • A distorted hoof shape and/or unusual rings. ...
  • An increased heart rate. ...
  • Too little—or too much—foot lifting. ...
  • Apparent stretched and/or bleeding laminae. ...
  • A shortened stride. ...
  • Increased insulin levels.

What is the fastest way to get rid of clover? ›

A simple strategy to get rid of it would be to apply a nitrogen-rich fertilizer to the clover patches. This will deter it from growing and spreading. A quick and affordable option is to use a fast-release fertilizer, which is especially recommended if you have a lot of clover to get rid of.

Should clover be removed? ›

Clover will begin to spread and grow in spring, so try and remove it before it flowers.

What is the best clover killer for pasture? ›

Clover is controlled best by TopShot Herbicide because it is selective and won't harm your desired turf.

What months are worse for laminitis? ›

Spring is traditionally known as a peak time for laminitis, but the latest research shows that the second biggest killer of horses and ponies is an all-year-round threat.

Is Magnesium Oxide good for laminitis in horses? ›

Essential for healthy brain and nerve function, Magnesium helps to promote equine hoof growth; support recovery after exercise; prevent laminitis in horses; and plenty more.

When should I turn my laminitic horse out? ›

When turning out laminitis-prone horses to graze, turn them out in the early morning and evening because that is when the water-soluble carbohydrate levels are lowest.

What feeds should be avoided in horses with liver dysfunction? ›

Feeding the horse with liver disease

Avoid feeds containing high levels of crude protein e.g. alfalfa, soyabean meal, clover. Avoid haylage. Avoid grains (other than cracked / flaked oats and maize). Some complete pure high fibre diet pellets are ok.

What are the signs of liver failure in horses? ›

The main signs are weight loss, poor appetite, depression, and lethargy. Jaundice, behavioral changes, diarrhea, light sensitivity, and bleeding are occasionally present. Fever may be persistent or intermittent. Microscopic examination of a liver biopsy is needed for a definite diagnosis.

What Herb is linked to liver damage? ›

In fact, some common herbs could cause toxic liver disease. Watch out for supplements that contain aloe vera, black cohosh, cascara, chaparral, comfrey, ephedra, or kava.

What hormone stimulates salivation? ›

Leptin. Leptin is a fullness hormone that works by telling your hypothalamus — the portion of your brain that regulates appetite — that you're full ( 18 ). However, people with obesity may experience leptin resistance.

What nerve controls saliva production? ›

The gland's productions are predominantly controlled by a nerve called the glossopharyngeal nerve which originates in the superior salivatory nucleus of the medulla in the brainstem.

What increases saliva production? ›

Chewing and sucking help stimulate saliva flow. Try: Ice cubes or sugar-free ice pops. Sugar-free hard candy or sugarless gum that contains xylitol.

How do I get my horse to stop drooling? ›

No treatment for slobbers is necessary except for changing the horse's food and limiting its access to pastures that contain infected fungi. Mowing the pasture can help control infected plants and promote healthy regrowth.

Why is my horse foaming and drooling? ›

It can be a sign of stress or exertion.

Excess saliva isn't only caused by relaxation, but it can be a symptom of poor riding or overexertion. A horse that is overworked may produce foam because that's the body's mechanism for trying to cool itself down quickly – necessary for a flight animal.

Why is my horse drooling and foaming at the mouth? ›

It is absolutely normal for a horse to secrete foamy saliva during physical exertion. In fact, this is often considered a positive physical trait because it indicates the horse is relaxed and being ridden correctly. In horses that are tense or have bad posture, the salivary duct is inhibited and their mouth dries out.

Does clover cause horses to drool? ›

If harboring sufficient fungal loads, white clover, alsike clover, alfalfa, ladino, and lespedeza can induce slobbering. The fungus produces slaframine, and it is this mycotoxin that actually provokes the extreme salivation.

What are the symptoms of high sugar in horses? ›

These include abnormal fat deposits, usually on the crest, rump and above the eye, excessive urinating and drinking, and potentially developing laminitis. However, if a horse displays these symptoms, it is not always because of insulin resistance.

What is the best hay for insulin resistant horses? ›

Hay for insulin-resistant horses

Timothy grass hay is a good choice for insulin-resistant horses because it tends to be lower in starch. Orchardgrass and Alfalfa are also great selections when you need to monitor the amount of starch your horse consumes.

What deficiencies cause excess saliva? ›

There are many causes of hypersalivation, including: cerebral palsy,neurodegenerative disorders, vitamin B3 deficiency, gastroparesis, pancreatitis, oral infections, rabies, many medications and several toxins. Hypersalivation is associated with either excess saliva production or decreased clearance.

How do you treat slobbers in horses? ›

For the vast majority of cases, slobbers is no more than a nuisance to horse owners. Access to fresh water will prevent dehydration and should always be provided. Other possible causes of excessive salivation can include mouth sores, foreign objects, and reactions to medication.

What are the symptoms of vesicular stomatitis in horses? ›

Symptoms include blister-like lesions on the tongue, mouth lining, nose or lips of an affected horse. Excessive salivation, difficulty in eating and swelling of the coronary band also may be seen. In some cases, the lesions develop on a horse's udder or sheath.

What neurological causes excess saliva? ›

Sialorrhoea is a frequent symptom of neurological diseases (e.g. Parkinson's disease, motor neuron disease, cerebral palsy, and stroke) and is defined as excessive saliva accumulation leading to unintentional loss of saliva from the mouth.

What infection causes excessive saliva? ›

Causes of Excessive Saliva

Hypersalivation in adults is primarily caused by: Mononucleosis or sinus infections. Strep throat or tonsillitis. Allergies.

What type of doctor treats hypersalivation? ›

Hypersalivation is best evaluated by a salivary gland specialist. These physicians are experts in diagnosis and treatment of rare and complicated disorders that affect the salivary glands.

What does selenium deficiency look like in horses? ›

Signs of Selenium deficiency may include muscle disease and wasting (frequently perceived as weight loss), impaired movement or difficulty getting up, difficulty swallowing, coughing when eating, respiratory distress and impaired heart function.

What are the signs of copper deficiency in horses? ›

One of the most obvious signs of potential copper deficiency is a change in coat colour due to loss of pigmentation. The coat might appear dull, frizzy or discolored with a reddish tinge. Copper deficiency can also cause anemia and weakened blood vessels, bones, or joints in adult horses.

What are the symptoms of piroplasmosis in horses? ›

Clinical Signs
  • Fever.
  • Reduced/Lack of Appetite.
  • Anemia (loss/destruction of red blood cells)
  • Jaundice (yellow discoloration of mucous membranes)
  • Exercise intolerance/Weakness.
  • Weight Loss.
  • Swollen Abdomen.
  • Labored Breathing.
Apr 13, 2022

Why is my horse drooling and won't eat? ›

Excessive salivation is a primary sign of stomatitis, along with a reluctance to graze or eat and a decrease in performance related to avoiding the bit. The causes of equine stomatitis and salivation can vary from mild and self-limiting to severe or even fatal in the case of rabies.

What does foaming at the mouth indicate? ›

If you say that someone is foaming at the mouth, you mean that they are very angry.

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