Breast Cancer Stages 0, 1, 2, 3 and 4 (2024)

Breast Cancer Stages 0, 1, 2, 3 and 4 (1)

At some point, your doctor will tell you what stageyour breast cancer is. Put simply, the stage describes how widespread or advanced the cancer is in the breast tissue and possibly other parts of your body. Determining the stage helps doctors explain the breadth of the cancer to you. Italso helps them determine how to move forward with treatment, including surgery, if needed.

Breast cancer is also classified according to other characteristics. These includehow sensitive it is to the hormones estrogen and progesterone as well as tothe level of certain proteins that play a role in breast cancer growth,such as HER2. It is also classified bythe cancer’s genetic makeup.Learn more about how specialists at MSK classify types of breast cancer.

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  • When and how does my doctor determine the stage of my breast cancer?
  • How many stages of breast cancer are there?
  • What is stage 0 breast cancer?
  • What is stage I (1) breast cancer?
  • What is stage II (2) breast cancer?
  • What is stage III (3) breast cancer?
  • What is stage IV (4) breast cancer?

When and how does my doctor determine the stage of my breast cancer?

Your doctor will assign a stage to your cancer after your physical exam and the initial results from your mammogram or other diagnostic imagingtest. The stagemay be adjusted after lab reports from your breast biopsy or surgery. In determining the stage of your cancer, your doctor will take into account what is called the T-N-M scale: T meaning tumor size;N relating to the involvement of nearby lymph nodes;and M referring to whether the cancer has metastasized (spread) beyond the breast to other partsof your body.

Learn more about the anatomy of your breast.

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How many stages of breast cancer are there?

There are five stages of breast cancer, starting at zero and going up to four. (They are represented by the Roman numerals I, II, III, and IV.)There are several variables within some stages.

Tumors are measured in millimeters and centimeters (ten millimeters equals one centimeter). For consistency here, we measure tumors in millimeters.

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What is stage 0 breast cancer?

This is the very beginning of the scale. It describes noninvasive breast cancers or precancers. This includes the most common form of noninvasive cancer, calledductal carcinoma in situ (DCIS). Within stage 0, there is no evidence that cancer cells or other abnormal cells have invaded neighboring normal tissue.

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What is stage I (1) breast cancer?

Stage I describes a very early stage of invasive cancer. At this point, tumor cells have spread to normal surrounding breast tissue but are still contained in a small area. Stage I is divided into two subcategories:

  • In stage IA, a tumor measures up to 20 millimeters (about the size of agrape), and there’s no cancer in the lymph nodes.
  • Stage IB can be described as either:
    • a small tumor in the breast that is less than 20 millimeters plus small clusters of cancer cells in the lymph nodes; or
    • no tumor in the breast plus small clusters of cancer cells in the lymph nodes.
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What is stage II (2) breast cancer?

Stage II describes cancer that is in a limited region of the breast but has grown larger. It reflects how many lymph nodes may contain cancer cells. This stage is divided into two subcategories.

Stage IIA is based on one of the following:

  • Either there is no tumor in the breast or there is a breast tumor up to 20 millimeters (about the size of agrape), plus cancer has spread to the lymph nodes under the arm.
  • A tumor of 20 to 50 millimeters is present in the breast, but cancer has not spread to the lymph nodes.

Stage IIB is based on one of these criteria:

  • A tumor of 20 to 50 millimeters is present in the breast, along with cancer that has spread to between one and three nearby lymph nodes.
  • A tumor in the breast is larger than 50 millimeters, but cancer has not spread to any lymph nodes.
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What is stage III (3) breast cancer?

In stage III breast cancer, the cancer has spread further into the breast or the tumor is a larger size than earlier stages. It is divided into three subcategories.

Stage IIIA is based on one of the following:

  • With or without a tumor in the breast, cancer is found in four to nine nearby lymph nodes.
  • A breast tumor is larger than 50 millimeters, and the cancer has spread to between one and three nearby lymph nodes.

In stage IIIB, a tumor has spread to the chest wall behind the breast. In addition, these factors contribute to assigning this stage:

  • Cancer may also have spread to the skin, causing swelling or inflammation.
  • It may have broken through the skin, causing an ulcerated area or wound.
  • It may have spread to as many as nine underarm (axillary) lymph nodes or to nodes near the breastbone.

In stage IIIC, there may be a tumor of any size in the breast, or no tumor present at all.But either way,the cancer has spread to one of the following places:

  • ten or more underarm (axillary) lymph nodes
  • lymph nodes near the collarbone
  • some underarm lymph nodes and lymph nodes near the breastbone
  • the skin
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What is stage IV (4) breast cancer?

Stage IV is the most advanced stage of breast cancer. It has spread to nearby lymph nodes and to distant parts of the body beyond the breast. This means itpossibly involvesyour organs — such as the lungs, liver, or brain — or your bones.

Breast cancer may be stage IV when it is first diagnosed, or it can be a recurrence of a previous breast cancer that has spread.

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Breast Cancer Stages 0, 1, 2, 3 and 4 (2024)

FAQs

Breast Cancer Stages 0, 1, 2, 3 and 4? ›

The earliest stage breast cancers are stage 0 (carcinoma in situ). It then ranges from stage I (1) through IV (4). As a rule, the lower the number, the less the cancer has spread. A higher number, such as stage IV, means cancer has spread more.

What is the difference between Stage 1 2 3 and 4 cancer? ›

Stage I through Stage III are for cancers that haven't spread beyond the primary tumor site or have only spread to nearby tissue. The higher the stage number, the larger the tumor and the more it has spread. Stage IV cancer has spread to distant areas of the body.

What is Stage 0 to Stage 4 breast cancer? ›

Breast cancer stage is usually expressed as a number on a scale of 0 through IV — with stage 0 describing non-invasive cancers that remain within their original location and stage IV describing invasive cancers that have spread outside the breast to other parts of the body.

What is Stage 0 and Stage 1 breast cancer? ›

Whereas Stage 0 is non-invasive breast cancer, Stage 1 breast cancer is invasive breast cancer. Stage 1 invasive breast cancer is early-stage breast cancer, where tumors are generally small and found to be in the early stages when it can be most effectively treated.

What is Stage 1 to 3 breast cancer? ›

Doctors may refer to stage I to stage IIA cancer as "early stage" and stage IIB to stage III as "locally advanced." Stage 0: Stage zero (0) describes disease that is only in the ducts of the breast tissue and has not spread to the surrounding tissue of the breast.

Is stage 4 cancer 100% death? ›

People with stage 4 cancer often live many years after diagnosis, which is why it's more accurate to describe it as "advanced" or "late-stage."

Has anyone survived stage 4 cancer? ›

To help shed light on this challenging condition, Ed, a husband, father and stage 4 non-small cell lung cancer (NSCLC) survivor, shared his journey from diagnosis to liver metastasis survivorship. In 2012, during a health screening, doctors found a concerning mass on Ed's liver.

Do you need chemo with stage 0 breast cancer? ›

Stage 0 breast cancer treatment doesn't typically include chemotherapy. If the abnormal cells are hormone receptor-positive, the next step may involve long-term treatment with a hormone-based drug.

What stage of breast cancer requires a mastectomy? ›

Mastectomy for breast cancer treatment

A mastectomy may be a treatment option for several types and stages of breast cancer, including: Stage 0 ductal carcinoma in situ (DCIS) or other noninvasive breast cancer. Stages 1 and 2 (early-stage) breast cancer. Stage 3 (locally advanced) breast cancer after chemotherapy.

Can you live 30 years with metastatic breast cancer? ›

Many women with metastatic breast cancer will live only a handful of years, says Hendershott. But about one-third will live at least five years after their diagnosis. And “there are people who have been living with stage IV breast cancer for more than 15 years,” she says.

Is mastectomy recommended for stage 0 breast cancer? ›

While mastectomy was once the gold-standard for Stage 0 DCIS breast cancer treatment, breast-conserving surgery (lumpectomy) is now more common.

What is the life expectancy of stage 0 breast cancer? ›

More than 98 percent of patients who are diagnosed with stage 0 breast cancer survive at least five years after their original diagnosis. While a few patients will experience recurrences, the survival rates are still encouraging.

How long does it take for stage 1 breast cancer to become stage 2? ›

On average, breast cancers double in size every 180 days, or about every 6 months. Still, the rate of growth for any specific cancer will depend on many factors. Every person and every cancer is different.

Do you need chemo for stage 1 breast cancer? ›

Chemotherapy. Chemotherapy is not usually offered for stage 1 breast tumours. It may be offered after surgery (called adjuvant therapy) for these tumours if there is a high risk that the cancer will come back (recur). Find out more about the risk of breast cancer recurrence and adjuvant therapy.

Where is the first place breast cancer usually spreads? ›

The sentinel lymph node

When cancer spreads, the lymph node located closest to the original tumor (the sentinel node) is usually affected first. In breast cancer cases, the sentinel lymph node is often located in the underarm area.

What stage is most breast cancer usually diagnosed at? ›

At the time of diagnosis, approximately 64% of breast cancer patients have local-stage breast cancer, 27% have regional stage, and 6% have distant (metastatic) disease.

Is Stage 3 cancer OK? ›

Stage 3 cancer is considered advanced. In this stage, the tumor may have grown to a specific size, the cancer may consist of multiple tumors, and/or the cancer may have spread to adjacent lymph nodes, organs or tissue.

Is Grade 3 cancer the same as Stage 3? ›

Tumor grade is not the same thing as cancer stage. Stage refers to how large a cancer tumor is and how far the cancer has spread. See Cancer Staging to learn more.

Is Stage 4 cancer the worst level? ›

Stage 4 is the most severe stage of cancer. Metastatic cancer is another name for this stage. It conveys that the cancer has metastasized — spread to distant areas of the body. Cancer is a group of diseases that cause rapid cell growth.

How long can you live with stage 4 cancer without treatment? ›

Stage 4 cancer usually has spread to multiple places in the body, meaning you can live only a few weeks or a few months. In rare cases, some people may survive for several months or even a year with stage 4 cancer, with or without treatment.

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